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E. H. Smith, M.D.
JAMA. 1898;XXX(13):741-742. doi:10.1001/jama.1898.02440650049010.
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Santa Clara, Cal., March 15, 1898.

To the Editor:  —In the Journal of March 12, 1898 (p. 621), Dr. J. O. Hirschfelder writes of "Oxytuberculin." In his article he states that "it was and is my desire that the doctrine of the curative effect of oxidized toxins should be most skeptically investigated, etc." That is just what I have been doing. The more I investigate the more skeptic I become, especially as regards "oxytuberculin." As to the Doctor not having "entered upon the field of animal experimentation, but limiting my work entirely to the clinical and bacteriologic sphere, etc.," I beg leave to call Dr. Hirschfelder's attention to plate 1, page 268 of the "Transactions of the Medical Society of the State of California" for 1897. This plate shows a dog upon whom the Doctor claimed to have experimented. The same plate, or one purporting to be the same, appeared


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