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EXPERIMENTAL INOCULATION OF MONKEYS WITH SYPHILIS, LEPROSY AND TUBERCULOSIS.

JAMA. 1905;XLIV(24):1932. doi:10.1001/jama.1905.02500510040005.
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In order to study disease in detail, especially those due to pathogenic organisms, experimental reproduction in animals is of the greatest importance. A brief consideration shows at once that, on the whole, those diseases that may be reproduced in animals are far better understood and controlled than those which can not thus be transmitted. It is, therefore, with much interest that we note the further success attained in the experimental inoculation of monkeys with syphilis.

In their last report, Metchnikoff and Roux1 describe their further experiments in this fertile field. Altogether they have inoculated ten chimpanzees with syphilitic virus from various sources and have obtained positive results in all cases. Successful results were obtained by using material from secondary lesions of the disease, as well as from the primary lesion, and one chimpanzee has been successfully inoculated from lesions of another, thus establishing the possibility of transmission from animal

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