L. W. SCHWAB, Ph.G., M.D.
JAMA. 1898;XXX(13):708-709. doi:10.1001/jama.1898.72440650016001d.
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My object in reporting this case is its rarity, difficulty of early recognition and the fact that two brothers died from this disease within thirteen months of each other.

I will first give the younger brother's case.

Mr. C., aged 55 years, married, Spanish descent, salesman in wholesale drygoods house.

Family history.  —Father is 82 years old and in good health, though he had a slight cerebral hemorrhage last winter, but entirely recovered. Mother died at 62 years of age, from fatty degeneration of heart and kidneys. The necroscopic report does not give any clue as to the cause. An elder brother died, at 57 years of age, from Addison's disease. One brother, still living, is 45 years old and in fair health. Two sisters died in childhood from scarlet fever.

Patient's history.  —Average weight 165 pounds, dark and sallow complexion and troubled with chronic constipation; moderate smoker and user


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