JAMA. 1898;XXX(13):701-705. doi:10.1001/jama.1898.72440650009001b.
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The gradual attainment of our present knowledge of the disease known as locomotor ataxia, is one of the fascinating stories of medicine. While it is undoubtedly true, as one writer says, that it is the most common and the best known today of all the nervous affections, and while it is also true that the advances made toward the recent conception of its etiology and pathology have within the last few years been something marvelous, it is nevertheless a fact that after all we have only entered upon its elucidation. Many of the newer discoveries have only added to the complexity of our knowledge. We are almost as much in the dark as ever in regard to the real cause or causes of the trouble, nor have we found as yet any sufficient reason why those causes should exert a selective action upon special nerve areas. One comprehensive definition has


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