According to statistics, acute articular rheumatism has its annual curve of highest frequency at the end of October and during November. Fortunately modern therapeutics has put us in a position to cope successfully, as a rule, with the worst symptoms of the disease. Old practitioners readily admit that they no longer see the prolonged agonizing sufferings in acute rheumatism which were not infrequent thirty or forty years ago, before the introduction of the salicylates. These remedies are not a specific for the disease, but if prescribed with due reference to the indications of the individual case they give symptomatic alleviation to the majority of patients.
About one in every eight cases of acute rheumatism, however, fails utterly to be relieved by the salicylates. Some of these after a period of primary relief refuse to progress beyond the slow running subacute state. A few of the obstinate cases will yield promptly