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JAMA. 1891;XVI(18):613-618. doi:10.1001/jama.1891.02410700001001.
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THE CHEMICAL FACTORS IN THE CAUSATION OF DISEASE.  A Course of Three Lectures delivered at the Post-Graduate Medical School of Chicago, March 26, 27 and 28, 1891.BY VICTOR C. VAUGHAN, M.D., Ph.D., OF ANN ARBOR, MICH.PROFESSOR OF HYGIENE AND PHYSIOLOGICAL CHEMISTRY AND DIRECTOR OF THE HYGIENIC LABORATORY IN MICHIGAN UNIVERSITY.LECTURE I. GENERAL CONSIDERATIONS OF THE RELATION OF BACTERIAL POISONS TO THE INFECTIOUS DISEASES.The majority of diseases may be grouped, from an etiological standpoint, into the following classes: 1. Traumatic; 2. Infectious; 3. Autogenous, and 4. Neurotic. It must be understood, however, that in many diseases the cause is not single, but multiple, and for this reason sharp lines of classification cannot be drawn. For instance, the greatest danger in those traumatic affections in which the traumatism itself does not cause death, lies in infection. The wound has simply provided a suitable point of entrance for the


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