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JAMA. 1890;XV(15):550-551. doi:10.1001/jama.1890.02410410030010.
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Atropine and Morphine to Combat the Noxious Effects of Chloroform—Interstitial Infections of Solution of the Bichloride of Mercury in the Treatment of Tumors—Treatment of Hæmorrhage due to Fibromata by preparations of Ergot of Rye and Hydrastis Canadensis.

Dr. Dastre has, for some time, undertaken experiments with a view of combating in the dog the noxious effects of chloroform, by the association of atropine and of morphine, and Dr. Aubert, of Lyons, was the first to endeavor to ascertain on man the advantages of this method. In a note by Dr. Reynier on the subject, which he read at a recent meeting of the Société de Chirurgie, he stated that he has employed this method in a certain number of cases in his service at the Hospital Tenon, and he has had one death, which he believes should be attributed to the association of these three elements.


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