JAMA. 1904;XLIII(25):1872-1873. doi:10.1001/jama.1904.02500250042004.
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After so many years of painstaking but fruitless studies of tumors by the ordinary microscopic methods, there seems little hope of discovering their specific cause in this way, and we must look for future progress chiefly along other lines of research. What line of research will be successful is the interesting question. Will it be one that is still unemployed, or is it perhaps among those newly brought to light? The recently developed methods of observation of bodies hitherto classed as "ultramicroscopic" seem rich in possibilities, for they represent simply an extension of methods, now familiar, which have been employed with success in solving so many problems. It has long been thought that in diseases apparently infectious, in which bacteria and protozoa could not be seen, the difficulty lay in the limit of magnification possible for our microscopes. The investigators who hold to the animal parasite etiology will hope for


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