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JAMA. 1904;XLIII(21):1539-1543. doi:10.1001/jama.1904.92500210001g.
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The relationship which exists between the functions of the digestive tract and that ensemble of biologic processes termed nutrition is both manifold and farreaching. It may perhaps be regarded as one of the shortcomings of the strictly "cellular" physiology of the century just closed that it failed to point out the conditions of interdependence and co-operation noticeable between different physiologic tissues. The modern organo-physiology is again beginning to emphasize a large number of such connections which have too frequently been overlooked, especially in a practical way. The physician should recognize in the study of alimentation something more than the mere consideration of the solvent action which the digestive secretions can exert. Thus Bidder and Schmidt wrote over fifty years ago in their classic work, 'Die Verdauungssäfte und der Stoffwechsel": "Wir finden einen zweiten und wesentlichen Theil der Bedeutung der Verdauungssäfte darin, dass sie Träger und Vermittler des innerhalb


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