JAMA. 1904;XLIII(18):1314-1315. doi:10.1001/jama.1904.02500180044013.
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A discussion of the subject is not proposed; only the recording of a note and a suggestion. The recent literature indicating some probability of the supreme etiologic rôle of hyperfunction of the adrenals in the production of arteriosclerosis has opened a wide field of physiologic and pathologic research. In addition to the experimental work necessary exactly to establish the causative relation of the adrenals to arterial disease, it is exceedingly desirable to have careful clinical observation of the early cases of arteriosclerosis. In no other line of work do physicians have the opportunity to observe the beginnings of any arterial disease as that which comes to the examiner for life insurance. He it is, almost solely, who every now and then has the chance carefully to examine arterial sclerosis in young men, and at its first stage. At this time it is usually overlooked by the examiner, because up to


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