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MYXEDEMA.

CAMPBELL P. HOWARD, M.D.
JAMA. 1907;XLVIII(17):1403-1408. doi:10.1001/jama.1907.25220430015001d.
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THYROID GLAND.  The size of the gland may be difficult to determine owing to the associated fulness of the neck. In a very considerable number of cases, however, there is a distinct diminution in the size of the gland. In 61 patients of my series in whom the condition of the gland is noted it was atrophied or not palpable in 46 (75.4 per cent.), in 3 of whom it was previously hypertrophied. In the London series it was atrophied in 22 of 59 cases (37.3 per cent.); in 3 it was also previously enlarged. Hun and Prudden10 found that the gland was diminished in size in 78 per cent, of their cases. In the London series there were 4 patients in whom there was definite hypertrophy at the time of the examination, which, with the 3 in each of the London and American series, in which there was

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