JAMA. 1907;XLVIII(12):1030. doi:10.1001/jama.1907.25220380046002d.
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When the first reports of the treatment of cancer with trypsin appeared I was greatly interested, as I had a patient with a large, rapidly growing tumor on the side of the neck. The condition was inoperable.

At first I used solutions of the trypsin powder, making sterile solutions of it and injecting them, but abandoned them as soon as I got the injectio trypsini, put up by Fairchild Brothers. I found that the directions for the treatment as published in The Journal1 by Dr. John Beard, the discoverer, cover every detail. Though the injections of trypsin were rather painful, I used injections of cocain in a few instances, but found that they did not diminish the pain materially.

Case 1.  —This patient was a man with a large vascular tumor, undoubtedly a sarcoma, on the side of the neck. Although the trypsin treatment is supposed to give good


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