JAMA. 1906;XLVII(20):1651-1652. doi:10.1001/jama.1906.25210200047002.
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For a number of years acetozone has been vigorously pushed in the treatment of typhoid fever, the manufacturers making the following claims:

  1. A greater freedom from intestinal disturbances such as characteristic odor of stool, diarrhea, tympanites, hemorrhage, perforation, peritonitis.

  2. A diminution of the toxemia, and the consequent improvement in physical and mental condition.

  3. The return to normal temperature more quickly.

  4. A modification of the course, severity, and type.

  5. Complications less frequent.

  6. Relapses less frequent.

  7. Recovery more prompt and certain.

We will see how far these claims are substantiated in a short series of 10 cases in which records have been kept; bearing in mind that the series is too short to indicate very much either way. All the patients in the series were treated by hydrotherapy with a milk diet. The acetozone solution contained from 15 to 20 grains to the quart, and was administered freely according to directions.



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