JAMA. 1896;XXVI(26):1249-1250. doi:10.1001/jama.1896.02430780001001.
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I invite your attention to some views in regard to the condition that has been designated as the precedent or pretubercular stage of consumption. That there is such a condition capable of distinct clinical position and recognition, is very generally conceded, though as to the exact nature of its underlying phenomena there remains much yet to be determined. We are not, however, without some useful and guiding data and such as we do possess has not received the consideration that the condition would appear to warrant.

We have reached a position where we can appreciate the discoveries and bearing of the work of Koch, and we realize the fact that these have not furnished the therapeutic resources that their first announcement seemed to promise. Influenced by this fact, investigation has been compelled to turn to other paths of work. The history of the pathology of tuberculosis has been varied. Our


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