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TOBACCO AND ARTERIOSCLEROSIS.

JAMA. 1906;XLVII(15):1197. doi:10.1001/jama.1906.02520150053005.
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The various studies of the causes of arteriosclerosis, particularly the purely clinical studies, have been so discordant in result that a certain amount of confusion regarding the etiology of this condition exists. As an example may be named the contrast between the general acceptance of the major rôle played by alcohol in the etiology of this disease, and the conclusions reached by Cabot in his study of the subject showing that alcohol, per se, had apparently little effect. There are a number of factors connected with the subject which render judgment of great difficulty. The variation in vulnerability of the vessels in different people is of great importance, as is the fact that in the complex conditions of modern life man is subjected to the action of a variety of poisons, either produced by himself or wilfully or unknowingly introduced from without. While it may be safe to assume that

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