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O. J. MINK, M.D.; N. T. McLEAN, M.D.
JAMA. 1906;XLVII(15):1166-1171. doi:10.1001/jama.1906.25210150022001e.
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Definition.  —Gangosa, a Spanish word meaning muffled voice, is the name employed by the Spaniards in the Ladrone and Caroline Islands to describe a disease characterized by a destructive ulceration, usually beginning on the soft palate, pillars or uvula, and extending by continuity to the hard palate and nasal cavity, larynx, and even to the face. Active ulceration is followed after a variable period by cicatrization or chronic ulceration. Mutilation always results. Constitutional symptoms are either slight or absent.

Synonyms.  Rhinopharyngitis mutilans (Leys). Ogo (Chamorro).

HISTORY AND GEOGRAPHY.  There is absolute proof that gangosa has existed in the Island of Guam for at least 150 years, and probably much longer. In 1828 the Spanish Royal Commission sent to investigate conditions in the Ladrone Islands reported gangosa as being prevalent and recommended that these cases and cases of leprosy and large ulcerations be isolated on one of the smaller islands


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