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Internal Administration of Antitoxic Sera.

Edward M. Merrins, M. D.
JAMA. 1906;XLVII(14):1119. doi:10.1001/jama.1906.02520140055025.
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East Orange, N. J., Sept. 21, 1906.

To the Editor:  —May I inquire if any readers of The Journal have administered antitoxic serum in other ways than by subcutaneous injection, and if so, what has been their experience? In England and elsewhere it has been demonstrated clinically that serum given per os or per rectum is effective, yet one seldom or never hears of these methods being practiced in this country. As the question is of considerable practical importance, it may be interesting to refer to some of the literature on the subject which justifies the change of method.Within the last few days it has been announced that Professor Behring's latest remedy against tuberculosis, called tulase, is about to be given an extensive trial in the hospitals of France and Germany, and, by his direction, it may be introduced into the system either by subcutaneous injection or by swallowing.


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