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JAMA. 1904;XLII(23):1461-1469. doi:10.1001/jama.1904.92490680001001.
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During the last ten years much work has been done in the etiology of malignant growths. While the representatives of pathology still cling to the cellular etiology of tumors, as it became established through the investigations of Virchow, Rokitansky and Cohnheim, clinicians have, on several occasions, proclaimed a germ as the cause of carcinoma or sarcoma. Up to the present time all these discoveries can not withstand criticism. It might appear convenient to find for every sickness and for every malignant growth a special germ, which we might destroy through the immunizing qualities of the animal body, and especially of the blood tissues. But we are still far from a solution of this problem, at least as long as the biology and physiology of the cell are covered with such a dark veil. All the growths, as we know, benign or malignant, follow a certain type, but in recent times


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