Wheelersburg, Ohio, March 27, 1896.
To the Editor:
—A most unfortunate and distressing accident occurred in the practice of Dr. S. S. Halderman, of Portsmouth, Ohio, on March 22, in connection with the use of antitoxin. A mild form of diphtheria was prevailing in the family of Mr. George Kricker, cashier of the Central Savings Bank, and the doctor administered the usual dose of antitoxin, as a prophylactic, to a little boy, 5 years old, in whom the disease had not yet appeared. The child, which had seemed to be in perfect health up to this time, was asleep when the injection was given, and in five minutes was a corpse. The doctor had withdrawn to another room to refill his syringe for use on another child, when the mother noticed the boy's lips puffing up and called to him that something was wrong with Willie. By the time the