JAMA. 1896;XXVI(11):535-536. doi:10.1001/jama.1896.02430630037006.
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Leukemia and other forms of essentially chronic blood disease are of more than ordinary interest because of their as yet unknown etiology. It would seem that not until their genesis is fully made clear can there be any reasonable chance for securing efficient therapeutic measures. Any observations that throw some new light upon such obscure diseases as leukemia are consequently of great value from a practical as well as from a theoretical point of view. Leukemia occasionally appears in the form of an acute disease. This manifestation might, if thoroughly studied, furnish some reliable indications as to the direction in which the solution of the etiologic problem referred to should be sought.

A. Fraenkel1 has recently published a series of articles upon the acute form of leukemia. He deals with the observations relative to six male and four female patients. The duration of the disease varied from twenty days


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