Prior to the dark ages we find little to indicate that typhoid fever was diagnosed as a distinct form of disease. When the mind of man awoke from the sleep of centuries a new impulse was given to all departments of science, and through the investigations of Spigelius, Sydenham, Huxham, Trousseau, Stoll, Petit, Peyer, Andral, Louis, Chomel, Bretonou and a host of others, we have our knowledge of typhoid or enteric fever, as a specific zymotic disease. Until within a very recent period the concensus of opinion has been that it could not be aborted, but must run a course, and whether only communicated from preexisting cases or occurring spontaneously, are still mooted questions. Virchow says, wherever we find a cell there must have been a cell—it is a concise statement of an almost universal belief, applicable to all forms of life since the monad, the microscopic atom of protoplasm