Since 1898, when I made the first announcement of the value of preparations of the suprarenal gland in the treatment of hay fever,1 I have made many observations on myself and others with a view to determine the best of these preparations and the best method of application and administration. I have also made observations with other promising palliatives, especially pollantin. The results may be summed briefly.
I. SUPRARENAL PREPARATIONS SYSTEMICALLY.
For some individuals, and in certain seasons, the systemic action of suprarenal preparations suffices to induce and preserve comparative comfort. The stomach, however, as I have previously pointed out, is not an eligible channel of administration. The medicinal substance must be absorbed from some other mucous membrane, where it can escape exposure to the digestive juices and the action of the liver. The eye, the tongue, the nose, the pharynx may be utilized. It was, and still is,