This work serves as a guide for the student in making laboratory experiments along the line of pharmacology. Experiments with many drugs are carried out and observed on animals. Only those preparations with which the student most commonly comes in contact are included in these experiments, such as the more important hypnotics, the cerebral and spinal excitants, the heart stimulants and depressants as demonstrated by their action on the heart of the turtle and dog. The effects of the suprarenal extract and the nitrites on the blood pressure may be demonstrated. The experiments for the most part are simple and practical and are of value in impressing the student with an accurate knowledge of the physiologic action of a drug in order that he may prescribe it in a proper therapeutic manner.