A correspondent has sent, for examination and comment, a pamphlet entitled "Illustrations of Human Vivisection," published apparently in Chicago by the "Vivisection Reform Society," an organization the avowed purpose of which is to make vivisection experiments a crime, except when under legal regulation. While the tone of the pamphlet is generally unjudicial and the author seems to have a strong personal bias against at least one prominent member of our profession, we are willing to assume for present purposes that ignorance, and not wilful malice, must have been the cause of some of his illegitimate inferences, not to use another designation. We would therefore say, for his information, that, in accounts of physiologic experiments, "toxic" does not mean lethal or even necessarily dangerous; that "inoperable," from a standpoint of cure, does not mean that operation to prolong life or to make the remnant easier is unjustifiable; that the administration of