The invention of a new technical method is often of the greatest importance for the advancement of our knowledge of the minute structure of the human and animal body, for a method once devised by a single investigator may be applied by hundreds of others to the solving of special problems. So important is the extension of technic that a number of the ablest investigators, among whom as especially noteworthy Carl Weigert of Frankfort may be mentioned, devote nearly all their time and energies to this phase of science.
Particularly in the study of the structure of the nervous system is the influence of the introduction of special methods easily discernible. As a matter of fact, most of our newer knowledge of neural anatomy can be grouped around the methods of Flechsig, of Weigert, of Marchi, of Golgi, of Nissl and the methods of Apathy and Bethe. Especially fruitful was