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RELATIONSHIP OF EPILEPSY TO CHRONIC GASTRO-INTESTINAL DISEASE.

G. W. McCASKEY, M.D.
JAMA. 1904;XLII(4):225-227. doi:10.1001/jama.1904.92490490010002c.
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ABSTRACT

While the pathology of epilepsy is, as yet, an unwritten chapter, there are several inferences which appear to me fairly well grounded. One of these is the existence of an organic defect in the finer and as yet inscrutable ultimate structure of the corticospinal neurons. Concerning the nature of this defect we are quite as much in the dark, but not any more so than we are with reference to the cognate defect which underlies hysteria. The assumption in both cases of such a fundamental deviation from the average normal type of construction of the nervous system, of the existence of inherent tendencies which are exceptional rather than typical, and which are possibly always inherited, or at least acquired during the early developmental period, appears to me absolutely necessary to explain why apparently identical causes will produce the clinical manifestations of these neuroses in one case and fail to do

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