The relations between the kidney and sugar excretion form interesting chapters in the study of diabetes and of less well-known glycosurias. The general conception that the kidney is practically passive in diabetes has been disputed. In 1897 Lépine1 reported the case of a woman dying in coma, whose blood contained 1.6 per cent, sugar and whose kidneys were enormous and showed a high grade of interstitial inflammation. Richter,2 in 1900, in a critical review of the relation between kidney and glycosuria, concluded that renal diseases may have a favorable effect on glycosuria, and that in kidney diseases the permeability of the renal filter to sugar seemed diminished. Von Noorden3 also considers that a diseased kidney shows a diminished permeability to sugar.
Weiland4 has shown that in cases of acute nephritis the blood-sugar level is low, and in chronic interstitial nephritis it reaches the upper limits of