JAMA. 1905;XLV(19):1403-1405. doi:10.1001/jama.1905.52510190039003.
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Patient.  —The young woman whose case is herewith reported has been under the care of my colleague, Dr. Ludwing Simon, for several weeks, and I acknowledge my indebtedness to him for the privilege of citation.

Family History.  —The patient is of Scotch-English descent, was born in Cambridge, England, is 24 years old, single, and at the present time a governess by occupation.It is interesting to note that Prof. Clifford Albutt diagnosed a carcinoma of the bowel in the paternal grandfather of the patient; a carcinoma of the larynx in an aunt on the maternal side, and an uncle on the maternal side is now afflicted with carcinoma of the bladder. This familial tendency to malignant neoplasms made the patient feel that, perhaps, her headaches and general enlargement were due to a similar growth. Her father, mother, one brother and two sisters are all living and well, though none of


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