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Charles E. Holzer, M.D.
JAMA. 1912;LVIII(21):1582. doi:10.1001/jama.1912.04260050258011.
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The following presents an unusually interesting blood-picture, and since the patient was followed to the autopsy table, the complete study seems worth reporting.

History.  —The patient was a man 04 years old, grocer, with unimportant family history except that father died of disease which answered description of a leukemia. Two sisters died of tuberculosis at middle age. Previous history was negative; the patient had had no previous illness except usual diseases of childhood. About March, 1910, he noticed a cough which became very persistent, but was not accompanied by expectoration. About the same time he noticed dyspnea on exercise. Both of the foregoing symptoms grew slowly but steadily worse. For two months previous to examination he had had pain at root of neck and difficulty, with some pain, in swallowing. Has been gradually losing weight for about one year, and for past six months has been growing constantly weaker and


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