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ANGIO-NEUROTIC EDEMA.

L. HARRISON METTLER, A.M., M.D.
JAMA. 1896;XXVII(17):904-906. doi:10.1001/jama.1896.02430950024002h.
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Though the pathology of angio-neurotic edema is still a mere theory and its treatment a source of continual disappointment, the affection itself is of sufficient importance and its occurrence of sufficient frequency to warrant further study. In the American Journal of Medical Sciences for December 1892, is an account of the disease, by Collins of New York, which is the most complete of the more recent descriptions. Dr. Collins' paper is based upon some seventy-five cases gathered from literature and personal observation; to which I can add two more, one having been under my care for about two years. The history of this case is as follows:

A married woman, 64 years of age, white, the mother of one child living. I was consulted by her in July, 1893. Her family history revealed nothing of special note. Her own general health had always been fairly good except for a certain

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