Of this work, which is to appear in six volumes, the first volume is now before us. The fundamental principle on which the work is based is the reference of symptomatology, diagnosis and treatment to the principles of pathologic physiology. This volume treats of infectious diseases, and after a statement of the general facts regarding infection and immunity, the special. diseases are taken up in detail. Much of this detail is made possible by the introduction of material in smaller type. The book is fully illustrated and contains somewhat extensive bibliographies for most of the articles. The present volume indicates that the work will be a useful addition to the numerous systems of medicine now before the profession.