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Tolerance of Infant to Codein

J. B. Kinne
JAMA. 1912;LVIII(3):213. doi:10.1001/jama.1912.04260010215022.
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To the Editor:  —An abstract on tolerance of infants to morphin in The Journal, September 9, p. 935, leads me to report the following experience: Six ¼-grain codein tablets were given the nurse, to be used in case of severe afterpains. None of these were used, but six weeks later the mother gave the child one tablet while being in town shopping and the child was quiet during the rest of the day and during a 16-mile ride home. One week later the child was again cross and received another tablet. I was called because they could not wake the child. It took me eighteen hours to do it; strychnin hypodermically (1/60 grain) and artificial respiration were used. I was unable to find out at that time what had been given the child, but two weeks later, after going through the same experience, I found out. I think the fact


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