Patient.
—M. S., an Austrian Polish Hebrew, aged 42, presser by occupation, was first seen April 12, 1909. Family history was negative for tuberculosis, Theumatism, gout, cancer, insanity and exophthalmos. The patient denied all venereal diseases. He used alcohol in large amounts, and had used it excessively since 10 years of'age, his average lately being four glasses of whiskey and ten glasses of beer a day. His present condition dated back for two years, when he noticed a swelling in both pectoral areas and a tumor the size of a pea on right and left sides of the back of the neck, which grew rapidly and very often caused him severe cramp-like pains in the affected areas. About a year before examination other masses appeared, situated below the occiput, and six months later, at the back of the neck, mammary areas, abdomen, back and arms. The masses on the arms