JAMA. 1912;LVIII(1):25-30. doi:10.1001/jama.1912.04260010027008.
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A subject involving so many questions, to be answered with our present incomplete knowledge of physiology, chemistry and pathology, must from necessity be far from solution. It is the object of this paper, from the recent work which has been done on the toxemias of pregnancy, to draw some conclusions as to where we stand in regard to the differentiation, treatment and prognosis of pernicious vomiting.

REPORT OF CASE  The following case of pernicious vomiting presents characteristics of the three theoretical types: reflex, neurotic and toxic, and is therefore presented:A woman, 29 years old, when married one month became pregnant. At about the fourth week vomiting began, and became so severe that in the tenth week, her physician deemed it necessary to induce abortion. It is interesting that a portion of the placenta was retained and that vomiting continued until this came away, a few days later.Five months


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