Having read with much interest Dr. Wynn's report1 of a case of acetanilid poisoning, I desire to give an experience somewhat similar which has come to my attention during the last few weeks:
—Mrs. W., aged 45, presented herself at my office for treatment, with a history of general malaise, drowsiness to the extent of falling to sleep while sitting at her work, marked fatigue with little exertion, numbness in her lower extremities, with a certain degree of interference with locomotion, the symptoms having come on gradually during the last few months. She had attributed the condition to "change of life" or malaria.
—There was a marked bluish-white palor and general puffiness of the skin, more marked below the eyes; her lips were of a dark blue color and the conjunctivæ a peculiar bluish-red. The nails were a blackish-blue and the veins beneath the tongue were greatly