JAMA. 1915;LXV(5):422-427. doi:10.1001/jama.1915.25810050003015.
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MISCELLANEOUS SOLUBLE SALTS  The systemic actions of a soluble salt are determined, as a rule, either by the anion alone or by the cation, but both ions are concerned in the actions of some salts.Sodium and potassium are of physiologic importance but we know little of their actions that would indicate that one should be used therapeutically rather than the other in any given condition. It is often stated, however, that certain important differences are observed between the actions of sodium bromid and those of potassium bromid.The rapid injection of large amounts of potassium salts directly into the circulation induces cardiac paralysis, but this action is not observed when the potassium salts are used therapeutically. It is sometimes maintained that the salts of ammonium or sodium should be used when cardiac depression from the action of potassium salts is to be feared.Lithium is of neither therapeutic


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