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JAMA. 1915;LXV(5):407-413. doi:10.1001/jama.1915.02580050035010.
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The cutaneous disorders which commonly involve the palms and soles are relatively few in number. Aside from eczema, the dry syphilodermas, particularly the tubercular and papulosquamous varieties, are probably the most frequent offenders. In both eczema and syphilis the palmar involvement may be dependent on the generalized distribution of the eruption, but in the later stages of both diseases the cutaneous manifestations are frequently confined to the flexor surface of the hands.

Of the palmar eruptions which are directly or indirectly due to the action of pyogenic organisms, infectious eczematoid dermatitis is the commonest, although dermatitis repens, including the acrodermatitis perstans of Hallopeau, is not unusual, and during the past year I have encountered three cases of granuloma pyogenicum in this region.

Of the various forms of dermatitis which may affect the palms as a result of the action of external irritants, that due to liquor formaldehydi is in my


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