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JAMA. 1894;XXII(16):574-578. doi:10.1001/jama.1894.02420950010001b.
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It is well known that the genital organs of the adult vertebrate are developed from two primitive organs of the embryo, the bodies named for Wolff and Müller; and that the sex of the individual varies with the relative development attained by these organs. In the future male animal the Wolffian duct furnishes the genital canal—epididymis and vas deferens—while the Müllerian duct suffers more or less complete atrophy; in the future female, on the other hand, the Müllerian duct furnishes the genital canal—Fallopian tubes, uterus and vagina (to the hymen)—the corresponding portions of the Wolffian duct suffering atrophy. In the most highly organized mammals, the male genital canal acquires certain accessory sexual glands not constantly found in the lower vertebrates—seminal vesicles, prostate, Cowper's, urethral and preputial glands—while the Miillerian duct exhibits marked atrophy; in man there persist regularly only the two rudimentary extremities of this duct, the hydatid of the


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