Owing to the small number of cases of this disease reported thus far, the following history may be of interest:
C. S., aged 35 years, single, school-teacher, has always been in rather delicate health, but has never been seriously ill. At the age of 22 years, she for the first time observed a tremor of the hands which recurred at intervals, especially when excited or exhausted from work. One year after the first appearance of the symptom, it became worse after an illness of several weeks duration. About eighteen months ago, after an exciting experience in connection with her school-work the tremor became more general, and has continued to grow worse more rapidly, ever since; so that she was finally compelled to discontinue her work on account of the annoyance caused by this distressing symptom.
She states that the tremor becomes more marked in the presence of strangers, and for