JAMA. 1885;V(4):99-100. doi:10.1001/jama.1885.04470020015003.
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Alterations in the Lymphatic Vessels in the Course of Syphilis.—1. The lymphatic system undergoes an almost constant alteration in the course of syphilis. But while the ganglia are quite often modified, the lymph-vessels, on the contrary, are very rarely so.

2. The lymphopathies exist under many conditions, and may be divided into six clinical forms: a. In the first place, there is a simple inflammatory lymphangitis consecutive to a specific ulceration, however excited. b. A lymphopathy may complicate the infecting chancre, and then it bears the same relation to the lymphatic vessels as the adenopathy consecutive to the syphilitic chancre bears to the lymphatic ganglia. c. There is observed a secondary disseminated lymphopathy, which evolves under the sole influence of the diathesis, without being under the dependence of a local manifestation. d. In the tertiary stage, certain lymphatics, principally those of the dorsum of the penis, may become sclerosed,


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