In 1871, at the Heidelberg Ophthalmological Congress, Horner described a disease of the cornea characterized by the appearance of numerous vesicles arranged in groups, accompanied by severe pain, photophobia, lachrymation and conjunctival irritation coincident, in many cases with herpes febrilis of the nose, lips, eyelids and other parts of the face. In the thirty-one cases observed by him, there was in every case some catarrh al inflammation of the respiratory passages, and in twenty-eight there was present a herpes of the nose or lips. To this affection Horner gave the name, "herpes febrilis cornea."
Inquiry as to the cause of this condition has been further prosecuted by subsequent writers, notably by Mile. Kendall a pupil of Horner, who in 1880, analyzed 115 cases from the Zurich clinic.
These were differentiated from Zoster and classed as herpes febrilis. As to the general diseases that were held to have some causal relation