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ARTICLE |

THE PRINCIPLES OF VACCINE THERAPY.

ALMROTH E. WRIGHT, M.D.
JAMA. 1907;XLIX(7):567-573. doi:10.1001/jama.1907.25320070037002f.
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CONDITIONS WHICH OBTAIN IN THE FOCI OF BACTERIAL INFECTION.  We may conveniently begin with the study of the conditions which obtain in foci of bacterial infection. I have already pointed out that the foci in which bacteria cultivate themselves are in every case "foci of lowered bacteriotropic pressure," and that the deficit of antibacterial substances in such foci can be accounted for by the facts that bacteriotropic substances are absorbed whenever blood fluids come in contact with bacteria, and that in the case of foci which are cut off from the blood stream the conveyance of bacteriotropic substances to the focus of infection by the lymph stream can only rarely keep pace with the absorption. This premised with regard to the conditions which are common to all bacterial foci, I may conveniently direct attention to special conditions which obtain in infections of serous membranes where serous effusion has taken place,

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