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William J. Gies
JAMA. 1917;LXVIII(17):1278. doi:10.1001/jama.1917.04270040266028.
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To the Editor:  —Of the making of dentifrices there appears to be no end. One of the latest of the patented products "to end the plaque" and "to save the teeth" is called "Pepsodent." This tooth paste, which is said to do "what was heretofore impossible," is now being widely advertised as an "efficient mucin digestant." Its sponsors claim that "Pepsodent," when applied to the teeth as a dentifrice, attacks the mucin plaques which are "the source of most tooth troubles," and that "Pepsodent attacks this plaque with pepsin." The individual tubes containing this paste, as it is put on the market, are labeled: "Pepsodent; proteolytic tooth paste (dental mucin digestant)." Advertisements in dental journals assert that "the whole object of Pepsodent is to dissolve the film" (mucin plaque).During the course of the research we have been conducting tinder the auspices of the First District Dental Society of the


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