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ARTICLE |

THE TREATMENT OF HODGKIN'S DISEASE

ARTHUR FENWICK HOLDING, M.D.; SAMUEL BROWN, M.D.
JAMA. 1917;LXVIII(9):701-704. doi:10.1001/jama.1917.04270030033011.
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In the past three years we have had under observation eighteen cases of Hodgkin's disease. In reviewing these cases an attempt will be made to present the results thus far obtained by the various methods of treatment. We shall also point out some of the clinical phases of the disease which have a bearing on the treatment. The diagnosis of each case was established by microscopic examination. The cases were all fully developed with lesions generalized throughout the body.

Although the claims of a specific diphtheroid organism as the cause of this disease as advanced by Negri and Mieremet,1 and Bunting and Yates2 have been disproved by Torrey,3 still the clinical evidences accumulated in the study of our cases, as from many other sources, point to the infectious origin of the disease and are in accord with the general opinion that the lesions are infectious granulomas. The first symptom noticed by

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