In the Phila. Med. Times of July 2, 1881, I published a case entitled "Remarkable Change in the Color of the Hair from Light Blonde to Black in a Patient while under Treatment by Pilocarpin. Report of a Case of Pyelo-Nephritis, with unusually prolonged Anuria." This Was a case of a lady, 25 years of age, and the drug was used to relieve the uræmic symptoms resulting from the anuria, which latter was extreme.
A record was kept of the amount of urine excreted, and this shows that on one occasion, from December 16 to December 23, a period of seven days, not a drop of urine was passed, and that from January 22, 1881, to February 2, eleven days, there was total anuria.
From January 22 to February 11 (twenty-one days), but 36 grams, or a little over 2 ozs. of urine were passed. During this time the catheter