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ARTICLE |

THE NATURE, MANNER OF CONVEYANCE AND MEANS OF PREVENTION OF INFANTILE PARALYSIS

SIMON FLEXNER, M.D.
JAMA. 1916;LXVII(4):279-283. doi:10.1001/jama.1916.02590040033009.
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ABSTRACT

The Rockefeller Institute for Medical Research has been appealed to by so many physicians and laymen for information and advice on the subject of infantile paralysis that it has seemed desirable to relate the facts of present knowledge concerning certain highly pertinent aspects of the disease, together with deductions of practical importance derived from them.

Nature.  —Infantile paralysis is an infectious and communicable disease which is caused by the invasion of the central nervous organs—the spinal cord and brain—of a minute, filterable micro-organism which has now been secured in artificial culture and as such is distinctly visible under the higher powers of the microscope.

Location of the Micro-Organism or Virus in the Sick.  —The virus of infantile paralysis, as the micro-organism causing it is termed, exists constantly in the central nervous organs and on the mucous membrane of the nose and throat and of the intestines in persons suffering from

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