JAMA. 1916;LXVI(26):2045-2051. doi:10.1001/jama.1916.02580520001001.
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The occasion brings to my mind an address which I heard, not in this noble hall, but in the building on the corner of St. Paul and Saratoga streets, nearly forty years ago. I had just graduated at the Maryland University, was working in the laboratory of Newell Martin in the Johns Hopkins University, and had come under the spell of the man and the place. The address by S. Weir Mitchell, a name equally renowned in medicine and literature, both in the subject matter and the grace of expression, made a deep and lasting impression on me. I very well remember the general subject concerned the renewal of the tissues, particularly the nervous tissue, after too great wear, and he showed the importance of exactly determining, not so much the nature of the disease as the condition of the diseased individual. He spoke also of the use of rational,


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