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WILLIAM O. OTT, B.S., M.D.; K. A. ROY, B.A., M.D.
JAMA. 1916;LXVI(11):800-802. doi:10.1001/jama.1916.02580370020008.
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Diphtheria carriers have always been a serious problem, and many methods to rid the unfortunate individuals of diphtheria organisms have been tried. The multiplicity of the forms of treatment advocated is proof of the unsatisfactory results obtained with any one method. Spraying the throat with cultures of Staphylococcus pyogenes aureus was at one time much in vogue. This proved to be too dangerous a procedure,1 and has been abandoned generally. Wood2 suggested and used a spray of Bacillus acidi lactici in the throat with good results. C. Hampsen Jones3 used Bolton's solution in the throat of carriers with some benefit. Hektoen and Rappaport4 advocate the use of kaolin in the nose and throat, and assert that the mucous membrane of these passages is almost rendered sterile by the use of this substance. Good results have been reported with the use of autogenous vaccines by some,5


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