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N. P. Yeardley, M.D.
JAMA. 1916;LXVI(9):650-651. doi:10.1001/jama.1916.02580350038016.
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Case 1. 

—History.  —Man, aged 37, white, merchant, height 5 feet 11 inches, weight 150 pounds, with unimportant family history, has had the ordinary diseases of childhood. He contracted gonorrhea eighteen years ago, which ran a protracted course. He had a crop of venereal warts which were cut off. Twelve years ago, his legs swelled, and his arms and legs were cold all the time. He had great trouble keeping warm. Accompanying these symptoms, a white urethral discharge, tenderness in the right hypochondrium, and pains in the lower abdomen developed. He was disturbed at night by painful and tingling sensations in the right arm. While at work he suffered from paroxysms of pain of a dull boring character, located in the epigastrium. These continued at semimonthly and monthly intervals over a period of two years, when deep jaundice developed. Following one of these attacks, in 1911, he was taken to


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