We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......


JAMA. 1911;LVI(3):177-179. doi:10.1001/jama.1911.02560030013005.
Text Size: A A A
Published online

In selecting cases for experimentation with "606" an attempt was made to choose those with demonstrable lesions and those which would best represent the various stages of the disease, excepting the meta- and parasyphilitic conditions.

The list of cases includes one with primary lesion of tonsil, one with primary lesion of penis with secondary eruption, two with maculopapular secondaries, one with ulcerating secondaries of the tonsils and vocal cords, and one with gummatous lesion of forehead. Except in one instance, an alkaline solution of the drug was injected into the buttocks according to the technic developed by Lesser.1 In this exception the same solution was injected intravenously, after being first diluted with distilled water to 200 c.c., according to Schreiber's method.2 The intragluteal injections gave very little pain at the time of administration except in one nervous individual. In every case the pain became quite severe within an


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.